Actor James Buckley, widely recognized for his role in the popular British sitcom The Inbetweeners, has undergone a significant health overhaul following a diagnosis that places him at a high risk for cardiovascular events. The revelation came during a conversation with his wife, Clair, where Buckley detailed the findings of a recent blood test that uncovered an elevated level of Lipoprotein (a).
Understanding Lipoprotein (a) and Its Implications
Lipoprotein (a), often referred to as Lp(a), is a specific type of cholesterol particle produced by the liver. It is genetically determined and plays a role in transporting cholesterol through the bloodstream. However, elevated levels of Lp(a) are associated with an increased risk of blood clots due to its tendency to make blood stickier. This condition can contribute to the buildup of plaque in arteries, a process known as atherosclerosis, thereby raising the likelihood of heart attacks, strokes, and other cardiovascular incidents.
Buckley shared that he was advised by medical professionals to make substantial changes to his diet and exercise routine. Expressing a common sentiment when faced with lifestyle adjustments, he humorously inquired if a medication option was available, to which Clair responded by pointing out his dietary habits, specifically mentioning KFC. Buckley countered that he had already begun making positive changes, including increased water intake and a reduction in unhealthy food consumption.
A Shift in Lifestyle Habits
The actor elaborated on the immediate changes implemented, noting that he and his wife had abstained from alcohol for two weeks and significantly reduced their consumption of takeaways. This dietary shift also led to an ironic personal reflection for Buckley. He admitted that he had previously criticized individuals who chose not to drink alcohol, labeling them as “boring.” Now, facing a doctor’s recommendation to limit or avoid alcohol, he felt a sense of cosmic timing, joking that perhaps a higher power was teaching him a lesson.
While Buckley stated his intention to resume drinking a beer “soon,” he emphasized that the current period was about implementing a “little reset” for his health. This period of personal reflection and lifestyle adjustment comes at a time of renewed public interest in The Inbetweeners.
The Inbetweeners: A Potential Comeback
Recent reports have circulated suggesting a potential reunion film for The Inbetweeners, with all four main stars – Simon Bird, Joe Thomas, James Buckley, and Blake Harrison – reportedly signing on for a new project on Netflix. This news follows a significant development from the production company Banijay, which announced in the autumn that it had secured a new deal with the show’s creators, Iain Morris and Damon Beesley. The agreement grants them the rights to revive the beloved series, which originally aired from 2008 to 2010 and was followed by two successful feature films, for a contemporary audience.
What is Lipoprotein (a)?
To provide further context on Buckley’s diagnosis:
- Genetic Inheritance: Lipoprotein (a) levels are primarily determined by genetics, meaning individuals inherit their predisposition from their parents.
- Structure: It is a modified form of low-density lipoprotein (LDL), commonly known as “bad” cholesterol, with an apolipoprotein(a) particle attached.
- Risk Factor: High levels of Lp(a) are considered an independent risk factor for cardiovascular disease, meaning it contributes to risk even in the absence of other common risk factors like high cholesterol, high blood pressure, or smoking.
- Monitoring: Unlike cholesterol levels, Lp(a) cannot be significantly altered by diet or exercise alone. Lifestyle changes are crucial for overall cardiovascular health but may not directly lower Lp(a) levels.
- Treatment: Currently, there are no universally approved medications specifically designed to lower Lp(a) levels. Research is ongoing, but management typically focuses on aggressively treating other modifiable risk factors such as blood pressure, LDL cholesterol, and promoting a healthy lifestyle.
Buckley’s Health Journey: A Broader Perspective
James Buckley’s candidness about his diagnosis and subsequent lifestyle changes serves as a powerful reminder of the importance of proactive health monitoring. While the genetic component of high Lp(a) means it’s not a matter of personal fault, as Buckley noted, the ability to mitigate associated risks through lifestyle adjustments and diligent medical care remains paramount. His decision to share his experience encourages others to be aware of their own cardiovascular health and to seek medical advice if they have concerns or a family history of heart disease.
The actor’s commitment to a healthier path, even amidst the buzz surrounding a potential Inbetweeners revival, underscores a personal dedication to well-being. His journey highlights that even individuals in the public eye face health challenges, and their willingness to discuss these issues can foster greater awareness and encourage positive action among their audience.

